Pearl
FDA-cleared AI for real-time dental radiograph analysis.
Overview
Pearl's Second Opinion is FDA-cleared dental imaging AI that analyzes radiographs in real time to flag caries, calculus, periapical radiolucencies, bone levels, and existing restorations. Pearl holds eight FDA 510(k) clearances for its Second Opinion family, from the original bitewing/periapical clearance (K210365, 2022) to caries contours (CC), caries segmentation (CS), pediatric caries, periapical radiolucency contours, bone level measurement (BLE), panoramic radiographs (2025), and CBCT anatomy segmentation (Second Opinion 3D). In 2026 it added Pearl Voice for ambient clinical notes and voice perio charting. Pearl says more than 29,000 practices have chosen it.
- +Eight FDA 510(k) clearances, covering 2D and 3D imaging
- +Used by 29,000+ practices (vendor-reported)
- +Strong patient case presentation visuals
- +Reduces variance between clinicians
- +Third-party listed starting price (~$299/month)
- -No public pricing from Pearl itself
- -Per-location monthly fees add up for groups
- -Integration specifics vary by PMS and imaging version
- -Outcome figures (e.g., "37% more disease") are vendor-reported
Features
Integrations
Articles that cover Pearl
FDA's Generative AI Device Paper: What It Means for the AI Tools Your Practice Uses (Comments Due Oct. 19)
On August 18, 2026, FDA published its first detailed sketch of how it might regulate generative AI medical devices: a two-axis risk map, clinician-style competency testing, and more postmarket monitoring. It is not guidance and binds no one yet. Here is what it says, where scribes, CDS, patient chatbots and imaging tools land, what the first 'patient-facing LLM' clearance actually covered, and which of the 26 questions clinicians should answer before the October 19 deadline.
AI Dental Scribes in 2026: Bola vs Kiroku vs the Voice Tools Built Into Overjet, Pearl, Videa, and Dentrix Ascend
In twelve months, three leading dental imaging AI companies and Dentrix Ascend shipped its own voice notes and perio charting. Here is how the standalone dental scribes compare with the bundled ones: where the data lands, what happens to the audio, what the research says about voice perio accuracy, and how to pilot one in your hygiene column.
Can You Bill for AI? Medicare Already Cut Your Pay for the Efficiency.
The FDA has authorized more than 1,300 AI-enabled medical devices. Medicare pays separately for about ten of them. Meanwhile CMS cut work RVUs 2.5% across most services on the theory that technology already made you more efficient. Here are the AI codes that actually generate payment in 2026, the taxonomy that decides which tools get one, and what the CY 2027 proposed rule would change.
FDA Just Moved the Line Between a Clinical Tool and a Regulated Device
In January 2026, the FDA rewrote its clinical decision support guidance and pushed more AI software outside its oversight. Single recommendations are now allowed, documentation tools got clearer footing, and generative AI got almost no framework at all. Here is what changed — and why 'no FDA clearance needed' tells you nothing about whether a tool works.
AI for Dental Practices in 2026: What's FDA-Cleared, What's Hype, and What's Worth Buying
Dental AI splits into two worlds: FDA-cleared imaging tools that read radiographs, and everything else. Knowing the difference protects you legally and clinically. We break down the FDA-cleared platforms, what they actually detect, real pricing, and how to evaluate dental AI without falling for marketing.